Attenuated radial augmentation index is associated with successful long-term antihypertensive treatment
نویسندگان
چکیده
منابع مشابه
Factors associated with increased radial augmentation index in hypertensive individuals.
BACKGROUND Arterial stiffness is a variable predictor of morbidity and mortality and a possible marker of vascular injury. Its non-invasive assessment by radial tonometry and analysis of the augmentation index (r-AI) allows identifying patients exposed to higher cardiovascular risk. OBJECTIVE To analyze the influence of r-AI on clinical-biochemical variables and its influence on the prevalenc...
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The augmentation index (AIx) and "oscillatory" compliance (C(2)) are wave contour analysis parameters for the central aorta (P(ao)) and radial artery pressure wave (P(rad)), respectively. Both are sensitive to cardiovascular risk factors such as aging, hypertension, and diabetes and have been proposed as prognostic markers for cardiovascular disease. In this work, we studied the relation betwee...
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OBJECTIVES Central hemodynamics may better represent the load imposed on the coronary and cerebral arteries and thereby bear a stronger relationship to cardiovascular outcomes. METHODS Patients who had confirmed hypertension as assessed by daytime 24-hour ambulatory blood pressure monitoring (≥135/85 mmHg) were enrolled. Central blood pressure and radial augmentation index (AIx) corrected for...
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Most forms of hypertension require life-long treatment; thus, it is important to determine the continuing effectiveness and safety of any new therapeutic agent. While participating in various investigational studies, 7103 hypertensive patients received captopril, of whom 4397 were treated for 3 months to 4 years. The 4-year patients included 2498 with mild or moderate essential hypertension (di...
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BACKGROUND Vascular dysfunction is highly prevalent if not ubiquitous in patients with hypertension. We compared two different measures of vascular function obtained from digital volume waveforms with measures of ventricular-vascular load derived from 24-hour blood pressure (BP) recordings in patients with hypertension. METHODS Digital pulsatile volume waveforms were captured via plethysmogra...
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ژورنال
عنوان ژورنال: Journal of Human Hypertension
سال: 2007
ISSN: 0950-9240,1476-5527
DOI: 10.1038/sj.jhh.1002278